Daily Current Affairs Update : 01 March 2023

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Human Immunodeficiency Virus

  • An old man from Germany, referred to as the Dusseldorf patient, has become at least the third person to have been “cured of HIV” with the virus not being detectable in his body even four years after stopping the medicine.
  • This was achieved with a bone-marrow transplant from people carrying a specific HIV-resistant genetic mutation.

What are the Other Reported Recoveries from HIV?

  • A Berlin patient became the first person to overcome HIV after receiving two stem cell transplants in 2007 and 2008 for his blood cancer.
  • The doctors selected a donor with a genetic mutation called CCR5-delta 32 that makes carriers almost immune to HIV.
  • In 2019, similar results were replicated in the London patient. Two more cases of successful treatment were reported in 2022.

What is CCR5-delta 32 Mutation?

  • Cysteine-cysteine chemokine receptor 5 (CCR5) is the main HIV co-receptor involved in the virus and cell-to-cell spread.
  • The CCR5 receptors on CD4 cells are used as a doorway by HIV. The CCR5-delta 32 mutation prevents these receptors from forming on CD4 cells, which effectively removes the doorway.
  • Only 1% of people worldwide have two copies of the mutation, and 20% carry one copy, mostly those of European descent.
  • What is Bone Marrow Transplant?
  • A bone marrow transplant is a medical treatment that replaces one’s bone marrow with healthy cells.
  • The replacement cells can either come from the person’s own body or from a donor.
  • A bone marrow transplant is also called a stem cell transplant or, more specifically, a hematopoietic stem cell transplant.

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Current Affairs Of the Day - 20 Dec 2022 :- Welcome to the Class24 Current Affairs website which provides you with the best compilation of the Daily Current Affairs 2022 taking place across the globe: National issues, International news, Sports covers, Science and Tech, Banking, Economy, Agreement, Appointments, Ranks and Report and General Studies.

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